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Oral Cholera Vaccine Vaxchora - posted 11/21/2016
The new oral cholera vaccine Vaxchora is now available in the US per the manufacturer, PaxVax. Travel Healthcare providers need to carefully assess the cholera risk of their traveling patients, because the vaccine is not needed by most travelers for whom the risk of exposure is low and can be reduced by taking care with food choices and by drinking safe beverages/water. The vaccine should be considered if travelers (for example, aid and healthcare workers) are going to work in an area where there has been a cholera outbreak, and people planing to stay long-term in an area of high risk, especially if their access to medical care is limited. The vaccine is FDA-approved for people ages 18 - 64. The efficacy studies PaxVax reports show 90% protection at a month, but a drop in protection over time. Adverse effects of the vaccine were similar to placebo with the exception of diarrhea which was 2% more likely with the vaccine. LEARN MORE

Vaxchora™ Clinical Data Summary - Advisory Committee on Immunization Practices, Atlanta 24 February 2016 can be found on the site at the following link:  which was added to the cdc site before the vaccine was FDA approved on June 10, 2016.

The FDA site has the package insert as well as approval information at:

PaxVax information on their site can be found at:

ZIKA - posted 8/3/2016

• Locally transmitted Zika cases in the US are currently limited to a small area north of Miami Florida and efforts are being made to kill mosquitoes in that area.

• The Aedes aegypti mosquitoes, which pass Zika and other viral diseases like Dengue, don't travel more than about 500 feet during their lifetimes, an encouraging fact.

• Local transmission was cited because none of the original 4 people had traveled to a Zika risk area, so they were exposed by a mosquito passing the disease from someone who did travel to a risk area and contracted the Zika disease.

• More cases have been reported this week and many cases go undetected because a large proportion of people do not have any symptoms when infected.

• One way the outbreak may be limited is that many people live in air conditioned homes which minimizes their risk.

• The mosquitoes that pass the disease are unlikely to go farther north than the deep south, Arizona and California.

• The CDC is coordinating current efforts to limit the spread of the disease. And the FDA has halted blood donations in S Florida until Zika screening is initiated.

• There are various opinions about how long pregnant women should avoid travel to the specific reported risk area.

The best resource for current information about the Zika virus can be found where the information is updated regularly.




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